2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions

Previous classifications of periodontitis were based on the 1999 International Workshop for a Classification of Periodontal Diseases and Conditions. Substantial new information has emerged from population studies, basic scientific investigations, and the evidence from prospective studies evaluating environmental and systemic risk factors of periodontal disease. The analysis of this evidence has prompted the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions to reclassify periodontitis.

This new classification has superseded older classifications. However, it may be wise to remain familiar with the older classification categories. The health of the patient’s periodontium may be assessed directly, from visible gingival inflammation (changes in appearance) and levels of plaque and calculus buildup. In health, the level of the free gingival margin should rest about 2-3mm coronal to the cemento-enamel junction (CEJ), and the epithelial attachment is found at or immediately adjacent to the CEJ. In health, the alveolar bone crest lies 1-2mm below the level of the CEJ. The distance between the start of the epithelial attachment and the crest of the alveolar bone is known as the biological width. The new periodontal classification system is broken down as the following:

1 – Necrotizing Periodontal Diseases. 

    • Necrotizing Gingivitis.
    • Necrotizing Periodontitis.
    • Necrotizing Stomatitis.

2 – Periodontitis as Manifestation of Systemic Diseases.

3 – Periodontitis.

    • STAGE – based on the severity and extent of distribution, as well as the complexity of management. “Stage” is a snapshot in time. Severity is primarily based on the interdental clinical attachment loss (CAL) at the worst site. Complexity is primarily based on additional local factors (furcation involvement, trauma, bite collapse etc.). 
      • Stage I – Initial periodontitis
        • 1-2mm CAL
        • ≤4mm probing depth
        • mostly horizontal bone loss
        • no teeth lost
      • Stage II – Moderate periodontitis
        • 3-4mm CAL
        • ≤5mm probing depth
        • mostly horizontal bone loss
        • no teeth lost
      • Stage III – Severe periodontitis with the potential for additional tooth loss
        • +5mm CAL
        • ≥6mm probing depth
        • ≥3mm vertical bone loss
        • furcation involvement Class II or greater
        • ≤4 teeth lost
      • Stage IV – Severe periodontitis with the potential for loss of the dentition
        • +5mm CAL
        • ≥6mm probing depth
        • ≥3mm vertical bone loss
        • furcation involvement Class II or greater
        • Occlusal trauma
        • Occlusal collapse, drifting, or flaring
        • ≥5 teeth lost, or ≤20 teeth remaining 
  • EXTENT (distribution). 
    • Localized – less than 30% of remaining teeth affected.
    • Generalized – more than 30% or remaining teeth affected.
    • Molar-incisor distribution.
  • GRADE – determined by the rate of progression, responsiveness to treatment, and the assessment of risk. Unlike staging, the grade is a dynamic measurement of how things are changing over time. 
    • Grade A – Slow rate of progression. 
      • No CAL in the past 5 years
      • %RBL/Age – less than 0.25
      • Minimal bone loss despite plaque buildup
      • Non-smoker
      • No diabetes
      • C-reactive protein less than 1mg/L
    • Grade B – Moderate rate of progression. 
      • ≤2mm CAL in the past 5 years
      • %RBL/Age – between 0.25 and 1.0
      • Bone loss consistent with plaque buildup
      • Smoker (less than 10 cigarettes per day)
      • Well controlled diabetes
      • C-reactive protein 1-3mg/L
    • Grade C – Rapid rate of progression. 
      • ≥2mm CAL in the past 5 years
      • %RBL/Age – more than 1.0
      • Excessive bone loss in light of plaque buildup
      • Smoker (more than 10 cigarettes per day)
      • Poorly controlled diabetes
      • C-reactive protein more than 3mg/L

To determine the periodontal classification, staging is often determined first and done by initially reviewing interdental CAL and choosing the appropriate rating based on the worst site. If CAL is not available, or to supplement this analysis, radiographic bone loss (RBL) can be used. The number of missing teeth is analyzed to modify the stage. Lastly, the presence of local factors are used to “upgrade” the stage as appropriate. Grade selection starts with the difference in CAL or RBL over the previous 5 years. Percentage radiographic bone loss to age (%RBL/Age) is a ratio of the patient’s age to the percentage bone loss visible radiographically. Case phenotype is a gauge of the progression of disease against what is expected. Smoking and diabetes places the patient in Grade B or C.

PREVIOUS CLASSIFICATIONS OF PERIODONTAL DISEASE

An age dependent classification of periodontal disease (adult periodontitis, juvenile periodontitis, early-onset periodontitis etc.) has largely been replaced by classification according to the clinical, radiographic, historical, and laboratory findings.

Aggressive periodontitis is an older classification of a destructive disease characterized by:

  • the involvement of multiple teeth.
  • a distinctive pattern of rapid attachment loss and bone destruction.
  • an early age of onset.
  • the absence of systemic diseases (otherwise healthy patients).
  • hyperresponsive macrophages, producing increased prostaglandin E2 (PGE2) and interleukin-1.

Aggressive periodontitis can be further classified according to its distribution:

  • Generalized form of aggressive periodontitis – usually occurs between 12 and 25 years of age and is characterized by rapid, severe destruction of the periodontal structures around most teeth. Episodic, rapid and severe attachment loss is seen. The generalized form is associated with a weak serum response and is most strongly associated with Prevotella intermedia and Eikenella corrodens.
  • Localized form of aggressive periodontitis – usually occurs between 8 and 22 years of age and is characterized by rapid, severe destruction of the periodontal structures around the incisors and first molars. There may be a relative lack of local factors (plaque) to explain the destruction. The localized form is associated with a strong serum response and is most strongly associated with gram-negative anaerobes Actinobacillus Actinomycetemcomitans and Capnocytophaga species. Prevotella intermedia and Eikenella corrodens are present but to a lesser extent.

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